Pain is a defense mechanism that alerts people to an upcoming danger or injury, thus alerting them to guard their bodies and not harm themselves any further.

Pain arises in all intensities, shapes and sizes. The most common type of pain is nociceptive pain, typically results from a physical injury. When you experience a cut on your finger, stub your toe or burn yourself, the nociceptive pain receptors gets activated. Another major classification is neuropathic pain which is produced by damage to any part of the nervous system.

Besides these, other forms of pain consist of breakthrough pain (transitory burst of pain in the setting of chronic pain), psychosomatic pain (complaint associated with psychological factors), incident pain, and pain insensitivity (unexpected alleviation or covering of pain).

How does pain work?

Different sensory nerve fibres are present in our body that may react to different physical stimuli, for example, a pin-prick, person's touch or running water. Our nerve fibres produce different chemical responses depending on the amount of the physical contact that in turn affect how the pain feelings are interpreted.

Once injured, the nociceptive pain receptors send pain signals into the spinal cord through the nerves, where the impulses ultimately make their way to the nervous system or brain. This all occurs within a fraction of seconds; these signals transfer through our bodies at a very fast rate.

Once the pain impulse reaches the brain, it travels straightaway to the thalamus (part of the brain involved in sensory perception), which consecutively communicates it to the other areas for current neurological and interpretation you are aware of. For instance, the cortex (the outermost or superficial part of the brain) is responsible for assuming the origin of pain and how it matches with the other kinds of pain. The thalamus, other than acting as a messenger, also aids an emotional reaction, resulting in frustration or anger.

Surprising and Tremendous Pain Solutions:

Generic Tramadol hydrochloride is an effective painkiller used to treat moderate to severe type of pain. It comes under various brand names such as Tramacip, Tramadol, Ultram, and Tramjet.

Mechanism of action:

Tramadol reduces the brain's sensitivity and response to pain signals. It also decreases the size or intensity of the pain impulse transmitted from one nerve to another.

Prescribed intake of Tramjet:

Tramjet is an orally administered drug available in the form of a tablet. It is typically taken every 4 to 6 hours as desirable. It is not necessary to have meals before taking this drug; you may also take it in empty stomach. Tramadol is a habit-forming drug, therefore should be taken exactly as directed. Do not take a larger dose or for a longer duration unless required.

Possible side effects

Contact your physician if any of these signs and symptoms get severe or do not go away: drowsiness, dizziness, blurred vision, headache, diarrhoea, and vomiting, upset stomach. The more severe side effects of this drug may include numbness or tingling of the hands and feet, fast heartbeat, seizures, redness, difficulty breathing, swelling, and itching of the face and changes in urination.


  • Do not give this drug to children below 16 years of age.
  • Avoid getting engaged in any kind of activity that demands attention like driving or performing heavy machinery work after taking this drug.
  • Do not take other opioid analgesics such as tranquillizers or hypnotics along with Tramadol or Ultram.
  • Stopping taking this medicine suddenly may result in serious withdrawal symptoms such as headache, nervousness, loose stools, shaking, nausea, sweating, agitation, shivering, or difficulty in sleeping, thus it is advisable not to discontinue this medicine without the consultation of your physician.
  • Avoid the intake of excessive alcohol along with Tramadol or Tramjet. If you are an alcohol addict, do not take this drug.
  • In case you are allergic to Generic Tramadol or hypersensitive to any other ingredients of Tramjet or Tramacip, then avoid taking these drugs.
  • Pregnant and breastfeeding women must not strictly use this drug as this drug may cause serious signs and symptoms in the foetus.
  • Tramadol causes drug dependency or addiction, even at fixed doses. Thus, it is advisable to take it precisely as allowed by your physician. The dose of this drug should not be altered as per your necessity.

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