Sildenafil Tablet is a well-known medication that is used in the management of erectile dysfunction in adult males. It is one of the best medications used for countering erection problem. It helps in improve the sexual performance in many males by maintaining a long lasting erection.
Sildenafil is a phosphodiesterase-5 (PDE-5) enzyme inhibitor that is accountable for the degradation of cGMP. Since Sildenafil inhibits PDE-5, it wards off the degradation of cGMP in the corpus cavernosum located around the male penile region. It prompts the release of nitric oxide from the endothelial cells and causes the synthesis of excess amount of cGMP. As the level of cGMP is amplified, it relaxes the smooth muscle cells and stimulates the desirable amount of flow of blood towards the male penile region. In this way, Sildenafil helps in maintaining a firm and a long lasting erection needed for intimacy.
Commercially, Sildenafil is available in a tablet dosage form with the dosing strengths of 50 mg, 100 mg, 150 mg and 200 mg. A patient should take one tablet of Sildenafil orally, approximately one hour before the lovemaking session with sufficient quantity of water. One tablet of Sildenafil begins its action within 30 minutes of its administration and that lasts for 4 to 5 hours. Therefore, you must maintain a difference of 24 hours between the two doses of Sildenafil. Only one tablet of Sildenafil should be administered in a day. You can take it with or without meals but avoid taking it with fatty and heavy meals.
Some common side effects of Sildenafil include dizziness, drowsiness, headache, muscle pain, back pain, indigestion, upset stomach, diarrhea, sore throat, flushing of the face, and stuffy nose.
Precautions while taking Sildenafil Tablet:
In case you observe any kind of allergic reactions to Sildenafil or any other component present in then you should stop taking this medication. Alcohol and grapefruit juice, when taken along with Sildenafil may increase side effects so consumption of these should be avoided. If you are taking nitrate drugs for the treatment of angina then you should not take Sildenafil, as there may be a sudden decrease in blood pressure. You should avoid taking fatty and heavy meals while taking Sildenafil as it may slow down the rate of absorption of the drug. Sildenafil is not indicated to be used in patients having age less than 18 and in women. Under severe medical conditions such as liver disease, bleeding disorder, cardiac problem, hemophilia, sickle cell anemia, Peyronie's disease, hypertension, stroke, coronary heart disease, retinitis pigmentosa, you should not consume Sildenafil.