Hepatitis B is a serious infectious ailment caused by the hepatitis B virus (HBV). It can cause acute and chronic liver infections and puts people at great risk of death from liver cirrhosis and liver cancer. Hepatitis B virus belongs to the family of viruses called Hepadnaviridae. Acute infection with Hepatitis B virus can make people suffer from these symptoms including loss of appetite, nausea, vomiting, body pains, mild fever, dark urine, and then growths to development of jaundice. Acute viral hepatitis generally lasts for a few weeks and then progressively improves in most affected people. Chronic infection with Hepatitis B may be allied with chronic inflammation of the liver and liver cirrhosis. This type of infection can dramatically enhance the occurrence of hepatocellular carcinoma. Hepatitis B virus is 50 to 100 times more infectious than HIV and its transmission occurs from contact to transmittable blood or body fluids enclosing blood. Hepatitis B virus, in general, exhibits its pathogenic effect by interfering with the functions of the liver by reproducing in hepatocytes. Acute hepatitis B infection does not usually need any treatment because most people overcome Hepatitis B infection naturally. On the other hand, treatment of chronic Hepatitis B infection requires certain medications like Hepsera to lessen the risk of cirrhosis and liver cancer.
Hepsera is a phenomenal antiviral medication extensively employed in the management of chronic hepatitis B in individuals who are 12 years of age or older. This medicine is not a permanent cure for hepatitis B infections, but it may reduce the amount of hepatitis B virus in the body. It offers relief from hepatitis B infections by inhibiting the virus ability to multiply in the body and infect new liver cells. Hepsera encloses an FDA-approved generic drug called Adefovir dipivoxil.
Adefovir dipivoxil is a potent prodrug of Adefovir. When it enters the body, it gets phosphorylated by cellular kinases to the active metabolite Adefovir diphosphate. It blocks the functioning of HBV DNA polymerase (reverse transcriptase) by opposing the activity of natural substrate deoxyadenosine triphosphate and by causing DNA chain conclusion after its amalgamation into viral DNA strands. This blocks the replication of hepatitis B virus, which further blocks the virus from multiplying in the body and infecting new liver cells.
Hepsera generally comes in an oral tablet form in dosing strength of 10mg. The dose recommended for the treatment of chronic hepatitis B in patients 12 years of age and older is that take one Hepsera 10mg tablet orally regardless of food, with a copious amount of water. People relying on the treatment of Hepsera should follow with frequent blood tests to evaluate the function of kidney or liver.
Malicious effects are produced while relying on the treatment of Hepsera such as mild stomach pain, diarrhea, gas, indigestion, weakness, headache, confusion, loss of appetite, vomiting, severe stomach pain, and pain in lower back.
Things to be remembered while using Hepsera:
Do not recommend Hepsera to patients who are allergic to generic Adefovir dipivoxil or other its other component. Contradict the use of Hepsera in patients who are relying on the treatment of Atripla, Complera, Stribild, Truvada, or Viread. Pregnant women and lactating mothers should not use Hepsera without consulting a doctor.
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