Clomid belongs to the class of medicines that is known as selective estrogen receptor modulator (SERM). Clomid is also known by the name Clomiphene. Clomid is used for the treatment of infertility problem in female and therefore it is also known as “Fertility drug “. Apart from this, Clomid is used for curing the problem of lactation, suprresion, ovulation induction, etc.
It helps in stimulating a good quantity of hormones that is required for growth and release of mature egg, a process known as ovulation. However, Clomid is not beneficial for those women whose ovary does not make eggs perfectly.
Clomid is also available in the market under the trade name of Androxal, Omifin and increases the production of gonadotropin by inhibition of negative feedback on the hypothalamus. Offered Clomid is available in the form of white & round tablet that is widely used in its citrate form for inducing ovulation. Clomid is given early in the menstrual cycle and ovulation occurs after 6-7 days of Clomid intake.
Clomid is white to pale yellow coloured tablet that is available in its citrate form. It is odourless and appears as crystalline powder that is freely soluble in methyl alcohol, soluble in ethanol, slightly soluble in water, acetone & chloroform and insoluble in ether. The molecular weight is 598.09 whereas C26H28ClNO • C6H8O7 is its molecular formula. Clomid contains various inactive ingredients such as sucrose, corn starch, lactose, magnesium stearate and pregelatinized corn starch.
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Clomid should be given to the patient in low dose of 50mg per day that is one tablet for 5 days. If the patient do not show any result of ovulation, then the dose should be increased.
Generally, Clomid is given to the female, however it is also effective for male where it is useful in secreting Luteinizing hormone(a hormone responsible for theproduction of male hormone, testosterone) that produces more sperm. Clomid is also used by the athletes who abuse anabolic steroids.
Clomid is administered orally with full glass of water and the dose is based on the medical condition of the patients.
If spontaneous bleeding occurs prior to therapy, then 50mg of Clomid is given for 5 days. If ovulation occurs at this dose then further dose should not be increased. However, if the ovulation does not occur at this dose then second dose of 100mg is given to the patients for 5 days. The maximum dose for 5 days should never be increased more than 100mg per day.
Sometimes, ovulation still does not occur after three course of therapy, thenClomid should be stopped for the patient and is revaluated. Additionally, if after three responses ovulation occurs still pregnancy has not occurred, treatment with Clomidis discontinued.
The intake of Clomid sometimes causes side effects in few patients. The user might suffer from pain in abdomen. Increase in appetite, constipation, rashes on skin, depression and diarrhoea.
Some patients may lose their hair, fatigue, dizziness, urine frequency increases, light-headedness and sudden increase or decrease in weight, vaginal dryness and nervous tension.
Prolonged use of Clomid may increase the serum level of desmosterol due to interference of cholesterol. Also, it increases the chances of invasive ovarian tumour.
Before taking Clomid, if the patient is allergic to any medicines, they should talk to the doctor.Allergic reaction may also be caused due to the inactive ingredients present in the tablet of Clomid.
If the patient is having any medical record, they must tell about this to the doctor. In case, the patient have cysts in the ovary, or enlarged ovary, abnormal vaginal bleeding, disease related to liver, uncontrolled thyroid gland problem, etc. they should consult doctor before taking Clomid drug.
Pregnant women should not take Clomid as it may pass to their breast milk and can harm the neonate. So she should consult their medical adviser.